According to Splenda's advertising, "Anywhere you can use sugar, you can use Splenda." I, personally, think Splenda is sweeter than most sweeteners, so I use less of it in my recipes, instead of equaling the amounts of sugar the recipe calls for.
Making a sweet baking mix for someone who needs to avoid sugar can be done by substituting Splenda for the sugar in the recipe. This is a page about gift mixes using Splenda.
